Use of QuantiFERON-TB Gold to determine the aetiology of idiopathic erythema induratum: A case report

Use of QuantiFERON-TB Gold to determine the aetiology of idiopathic erythema induratum: A case report

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Although rare, erythema induratum is the most common entity presenting as lobular panniculitis with vasculitis.It is usually caused by a hypersensitivity reaction to Mycobacterium tuberculosis , although other aetiologies have been reported.We present a case of ilootpaperie a 73-year-old male with multiple recurring tender erythematous nodules on the backs of both calves and shins.Prior to arrival in our clinic, the patient underwent a 9-month course of isoniazid with no improvement and subsequently received a diagnosis of idiopathic erythema induratum.We performed an interferon-gamma release assay QuantiFERON-TB Gold elbeco adu ripstop pants which was positive for M.

tuberculosis infection.The patient was successfully treated with ethambutol 1.6 g for 1 month; pyrazinamide 2 g for 2 months; and isoniazid 300 mg, vitamin B6 25 mg, and rifampin 600 mg for 6 months.This case highlights the utility of using interferon-gamma release assay QuantiFERON-TB Gold and a multidrug regiment over isoniazid in erythema induratum.